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A small but statistically significant reduction of growth rate from 7. These were nausea, acne, pain in an extremity, increased alanine transaminase and aspartate transaminase, and allergic dermatitis. Following 1 mg once daily multiple administration in pediatric patients, the mean time to reach the maximum Anastrozole concentration was 1 hr. The terminal elimination half-life was Based on a population pharmacokinetic analysis, the pharmacokinetics of Anastrozole was similar in boys with pubertal gynecomastia and girls with McCune-Albright Syndrome. Response rates and time to progression were similar for the over 65 and younger patients. Dosage adjustment in patients with renal impairment is Legal Anadrol for sale in Australia necessary [ see Dosage and Administration 2. The plasma Anastrozole concentrations in the subjects with hepatic cirrhosis were within the range of concentrations seen Legal Anadrol for sale in Australia normal subjects across all clinical trials. Therefore, dosage adjustment is also not necessary in patients with stable hepatic cirrhosis. Anastrozole has not been studied in patients with severe hepatic impairment [ see Dosage and Administration 2. Clinical trials have been conducted with Anastrozole, up to 60 mg in a single dose given to healthy male volunteers and up to 10 mg daily given to postmenopausal women with advanced breast cancer; these dosages were tolerated. A single dose of Anastrozole that results in life-threatening symptoms has not been established. There is no specific antidote to overdosage and treatment must be symptomatic. In the management of an overdose, consider that multiple agents may have been taken. Vomiting may be induced if the patient is alert. Dialysis may be helpful because Anastrozole is not highly protein bound.



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